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Published on 28 October 2024

Alzheimer's research: Superspreader fibrils caught in the act

Dübendorf, St. Gallen und Thun, 28.10.2024 - In dementia diseases such as Alzheimer's, incorrectly folded proteins accumulate in the brain. Empa researchers have now resolved a particularly active species of protein fibrils with unprecedented precision. The formation of potentially toxic molecules on the surface of protein fibrils was studied from early to late stages spanning over a period of hours. The researchers recently published their results in the journal Science Advances.